The combination of the two drugs reduces the HER2-positive breast cancer in 11 days

The Scientists from the Institute of cancer research, (London) the University of Manchester and the University Hospital of South Manchester NHS Foundation Trust, has found an interesting revelation about breast cancer. Their exhaustive research on a group of women who suffer from malignant tumors of breast cancer found that a combination of two drugs on lapatinib and trastuzumab (Herceptin) can effectively shrink tumors HER2 cancer affected women in 11 days. The result is a pretty compelling and drew attention to the world.

The test was applied to EPHOS (B) 256 women suffering from HER2-positive breast cancer. Then the women were in the phase between initial diagnosis and surgery to remove the tumors. With 256 women were divided into three groups. They were being treated for 11 days before their operation. Initially, the products are administered to patients in a random manner. So while some were given lapatinib, trastuzumab some were given, some got a combination of both, and others were given no treatment at all.

Half way between the test sessions, patients taking a combination of the both drugs began to appear more responsive. It has been observed that 17 percent of the women taking both drugs had only minimal residual disease. Is defined as the invasive tumor, which is usually less than 5 mm in size. 11% had a pathological complete response which means that no biological mark of the invasive tumor can be found in the breast.

The trial Co-leader Professor Judith Bliss, Director of the Cancer Research UK-funded clinical trials and the statistics unit in ICR, said! our trial set, to try to use the window between diagnosis and surgery to find traces of that combined treatment with trastuzumab 'em and lapatinib, have a biological effect on HER2 positive tumors. So it was unexpected to see quite such a dramatic response to trastuzumab and lapatinib in 11 days.

Our results are a strong foundation on which you can build additional studies of the combined anti-HER2 therapy before surgery which could reduce the number of women that require subsequent chemotherapy, which is also very effective, but can lead to long-term side effects.

Comments

Top social tech firms urged to step up online abuse fightback

The top tech companies are talking to grassroots organisations across the globe to organise a fightback on their platforms against online abuse, hate speech, misogyny and stalking. The famous social networks Facebook, Twitter and Google are reaching out to women’s groups, NGOs and communities in Africa, America, Europe and the Middle East as the scale of abuse online continues to increase. So these attempts to foster a (counter-speech) movement to challenge the violent misogyny, racism, threats, intimidation and abuse that flood social media platforms have prompted some of the communities they are trying to empower to question whether they are ducking their own responsibilities. A fomous actor said, of the End Violence against Women coalition, ( Any moves by social media companies to support, encourage and empower individuals and groups to resist and counter abuse is very welcome ). So the facebook’s US-based head of global safety, Antigone Davis, has recently overseen a series...

Instagram unveils new logo, but it's not quite picture perfect | TheNews Linzer

Photo sharing app unveils new sunset-coloured logo and a sleeker in-app look, but opinion is mixed Instagram, the photo sharing app owned by Facebook, responsible for such cultural highlights as hot-dog legs, The Fat Jewish memes and Rich Kids of, well, Instagram, has debuted a new logo. The previous one, a retro-looking camera, and one of the most recognisable tech logos out there, has been replaced by a background swirl of sunset colours (orange, yellow, pink, purple) and a white outline of a camera. As if the camera was murdered, and chalk was drawn around its body. Murdered at sundown. Here it is: The new logo was announced via a blog post, a longer post on Medium from head of design, Ian Spalter, and also a short introductory film. The kind that is usually intensely annoying, but actually this one is quite cute (warning though: the end has a lot of flashing and intense colours). Continue reading... Published By - Theguardian.com- Tech News, Politics news, UK and world politic...

Over 40M people of Irish descent are in the United States, 8x more than the population of Ireland

The Irish people (Irish: Muintir na hÉireann or Na hÉireannaigh) are a nation and ethnic group native to the island of Ireland, who share a common Irish ancestry, identity and culture. Ireland has been inhabited for about 9,000 years according to archaeological studies (see Prehistoric Ireland). For most of Ireland's recorded history, the Irish have been primarily a Gaelic people (see Gaelic Ireland). Anglo-Normans conquered parts of Ireland in the 12th century, while England's 16th/17th century (re)conquest and colonization of Ireland brought a large number of English and Lowland Scots to parts of the island, especially the north. Today, Ireland is made up of the Republic of Ireland (an independent state), and the smaller Northern Ireland (a part of the United Kingdom). The people of Northern Ireland hold various national identities; including Irish, Northern Irish, British, or some combination thereof. The Irish have their own customs, language, music, dance, sports, cuisine,...

Bol News

Search This Blog